| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PYGM |
| Gene ID: | 5837 |
| Uniprot ID: | PYGM_HUMAN |
| Immunogen Region: | 743-842 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 743-842 of human PYGM (NP_005600.1). |
| Immunogen Sequence: | IEQLSSGFFSPKQPDLFKDI VNMLMHHDRFKVFADYEDYI KCQEKVSALYKNPREWTRMV IRNIATSGKFSSDRTIAQYA REIWGVEPSRQRLPAPDEAI |
| Post Translational Modifications | Phosphorylation of Ser-15 converts phosphorylase B (unphosphorylated) to phosphorylase A. |
| Function | Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis. |
| Protein Name | Glycogen Phosphorylase - Muscle FormMyophosphorylase |
| Database Links | Reactome: R-HSA-70221 |
| Alternative Antibody Names | Anti-Glycogen Phosphorylase - Muscle Form antibodyAnti-Myophosphorylase antibodyAnti-PYGM antibody |
Information sourced from Uniprot.org