Anti-PYGB antibody (544-843) (STJ28485)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PYGB (544-843) antibody for use in WB, IF, ICC, IP and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/IP/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PYGB |
| Gene ID | 5834 |
| Uniprot ID | PYGB_HUMAN |
| Immunogen Region | 544-843 |
| Immunogen Sequence | LKFSAFLEKEYKVKINPSSM FDVHVKRIHEYKRQLLNCLH VVTLYNRIKRDPAKAFVPRT VMIGGKAAPGYHMAKLIIKL VTSIGDVVNHDPVVGDRLKV IFLENYRVSLAEKVIPAADL SQQISTAGTEASGTGNMKFM LNGALTIGTMDGANVEMAEE AGAENLFIFGLRVEDVEALD RKGYNAREYYDHLPELKQAV DQISSGFFSPKEPDCFKDIV NMLMHHDRFKVFADYEAYM |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 544-843 of human PYGB (NP_002853.2). |
Additional Info
| Post Translational Modifications | Phosphorylated. Phosphorylation of Ser-15 converts phosphorylase B (unphosphorylated) to phosphorylase A. |
| Function | Glycogen phosphorylase that regulates glycogen mobilization. Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. |
| Protein Name | Glycogen Phosphorylase - Brain Form |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-70221 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Glycogen Phosphorylase - Brain Form antibodyAnti-PYGB antibody |
Information sourced from Uniprot.org