| Host: | Rabbit |
| Applications: | WB/IF/ICC/IF-P/IHC-P/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | SRM14983 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Purification: | Affinity purification |
| Dilution Range: | WB, 1:12000-1:72000IF/ICC, 1:200-1:2000IF-P, 1:200-1:2000IHC-P, 1:200-1:800ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PYCR1 |
| Gene ID: | 5831 |
| Uniprot ID: | P5CR1_HUMAN |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. |
| Function | Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H. At physiologic concentrations, has higher specific activity in the presence of NADH. Involved in the cellular response to oxidative stress. |
| Protein Name | Pyrroline-5-Carboxylate Reductase 1 - MitochondrialP5c Reductase 1P5cr 1 |
| Database Links | Reactome: R-HSA-8964539 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Pyrroline-5-Carboxylate Reductase 1 - Mitochondrial antibodyAnti-P5c Reductase 1 antibodyAnti-P5cr 1 antibodyAnti-PYCR1 antibody |
Information sourced from Uniprot.org

