Anti-PXYLP1 antibody (201-251 aa) (STJ194959)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human ACPL2 at the amino acid range 201-251
General Information
| Short Description | Rabbit polyclonal anti-2-phosphoxylose phosphatase 1 (201-251 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PXYLP1 |
| Gene ID | 92370 |
| Uniprot ID | PXYP1_HUMAN |
| Immunogen | Synthesized peptide derived from the human ACPL2 at the amino acid range 201-251 |
| Immunogen Region | 201-251 aa |
| Specificity | This antibody detects endogenous levels of ACPL2 at Human/Mouse/Rat |
Additional Info
| Function | Responsible for the 2-O-dephosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature glycosaminoglycan (GAG) chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O-dephosphorylation during completion of linkage region formation is a prerequisite for the initiation and efficient elongation of the repeating disaccharide region of GAG chains. |
| Protein Name | 2-Phosphoxylose Phosphatase 1Acid Phosphatase-Like Protein 2Xylosyl PhosphataseEpididymis Luminal Protein 124 |
| Database Links | |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane ProteinColocalizes To Golgi Apparatus In A B3gat3-Dependent Manner |
| Alternative Antibody Names | Anti-2-Phosphoxylose Phosphatase 1 antibodyAnti-Acid Phosphatase-Like Protein 2 antibodyAnti-Xylosyl Phosphatase antibodyAnti-Epididymis Luminal Protein 124 antibodyAnti-PXYLP1 antibodyAnti-ACPL2 antibodyAnti-HEL124 antibodyAnti-XYLP antibodyAnti-UNQ370 antibodyAnti-PRO706 antibody |
Information sourced from Uniprot.org