| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PTPRO |
| Gene ID: | 5800 |
| Uniprot ID: | PTPRO_HUMAN |
| Immunogen Region: | 30-300 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-300 of human PTPRO (NP_109592.1). |
| Immunogen Sequence: | FHVTVQDDNNIVVSLEASDV ISPASVYVVKITGESKNYFF EFEEFNSTLPPPVIFKASYH GLYYIITLVVVNGNVVTKPS RSITVLTKPLPVTSVSIYDY KPSPETGVLFEIHYPEKYNV FTRVNISYWEGKDFRTMLYK DFFKGKTVFNHWLPGMCYSN ITFQLVSEATFNKSTLVEYS GVSHEPKQHRTAPYPPQNIS VRIVNLNKNNWEEQSGNFPE ESFMRSQDTIGKEKLFHFT |
| Tissue Specificity | Glomerulus of kidney. Also detected in brain, lung and placenta. |
| Function | Possesses tyrosine phosphatase activity. Plays a role in regulating the glomerular pressure/filtration rate relationship through an effect on podocyte structure and function. |
| Protein Name | Receptor-Type Tyrosine-Protein Phosphatase OR-Ptp-OGlomerular Epithelial Protein 1Protein Tyrosine Phosphatase U2Ptp-U2Ptpase U2 |
| Database Links | Reactome: R-HSA-9034015 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Receptor-Type Tyrosine-Protein Phosphatase O antibodyAnti-R-Ptp-O antibodyAnti-Glomerular Epithelial Protein 1 antibodyAnti-Protein Tyrosine Phosphatase U2 antibodyAnti-Ptp-U2 antibodyAnti-Ptpase U2 antibodyAnti-PTPRO antibodyAnti-GLEPP1 antibodyAnti-PTPU2 antibody |
Information sourced from Uniprot.org