| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Receptor-type tyrosine-protein phosphatase kappa (180-260 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PTPRK |
| Gene ID: | 5796 |
| Uniprot ID: | PTPRK_HUMAN |
| Immunogen Region: | 180-260 aa |
| Specificity: | PTPRK Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 180-260 |
| Post Translational Modifications | This protein undergoes proteolytic processing. |
| Function | Regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. Negative regulator of EGFR signaling pathway. Forms complexes with beta-catenin and gamma-catenin/plakoglobin. Beta-catenin may be a substrate for the catalytic activity of PTPRK/PTP-kappa. |
| Protein Name | Receptor-Type Tyrosine-Protein Phosphatase KappaProtein-Tyrosine Phosphatase KappaR-Ptp-Kappa |
| Database Links | Reactome: R-HSA-182971 |
| Cellular Localisation | Cell JunctionAdherens JunctionCell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Receptor-Type Tyrosine-Protein Phosphatase Kappa antibodyAnti-Protein-Tyrosine Phosphatase Kappa antibodyAnti-R-Ptp-Kappa antibodyAnti-PTPRK antibodyAnti-PTPK antibody |
Information sourced from Uniprot.org