• Immunofluorescence analysis of NIH-3T3 cells using PTPN13 Polyclonal Antibody (STJ114974) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
  • Western blot analysis of Mouse heart, using PTPN13 Rabbit polyclonal antibody (STJ114974) at 1:5000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 60s.

Anti-PTPN13 antibody (250-500) (STJ114974)

SKU:
STJ114974

£112.50 - £522.50
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Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PTPN13 (250-500) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:2000-1:6000
IF/ICC 1:50-1:100
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PTPN13
Gene ID: 5783
Uniprot ID: PTN13_HUMAN
Immunogen Region: 250-500
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 250-500 of human PTPN13 (NP_542416.1).
Immunogen Sequence: QDENYFKDILSDNSGREDSE NTFSPYQFKTSGPEKKPIPG IDVLSKKKIWASSMDLLCTA DRDFSSGETATYRRCHPEAV TVRTSTTPRKKEARYSDGSI ALDIFGPQKMDPIYHTRELP TSSAISSALDRIRERQKKLQ VLREAMNVEEPVRRYKTYHG DVFSTSSESPSIISSESDFR QVRRSEASKRFESSSGLPGV DETLSQGQSQRPSRQYETPF EGNLINQEIMLKRQEEELM
Tissue Specificity Expressed in keratinocytes (at protein level). Present in most tissues with the exception of the liver and skeletal muscle. Most abundant in lung, kidney and fetal brain.
Function Tyrosine phosphatase which regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling. May regulate phosphoinositide 3-kinase (PI3K) signaling through dephosphorylation of PIK3R2.
Protein Name Tyrosine-Protein Phosphatase Non-Receptor Type 13
Fas-Associated Protein-Tyrosine Phosphatase 1
Fap-1
Ptp-Bas
Protein-Tyrosine Phosphatase 1e
Ptp-E1
Hptpe1
Protein-Tyrosine Phosphatase Ptpl1
Database Links Reactome: R-HSA-1660499
Reactome: R-HSA-9008059
Reactome: R-HSA-9696264
Reactome: R-HSA-9696270
Reactome: R-HSA-9696273
Cellular Localisation Cytoplasm
Cytoskeleton
Nucleus
Cell Projection
Lamellipodium
Colocalizes With F-Actin
Colocalizes With Pkn2 In Lamellipodia-Like Structure
Regions Of Large Actin Turnover
Alternative Antibody Names Anti-Tyrosine-Protein Phosphatase Non-Receptor Type 13 antibody
Anti-Fas-Associated Protein-Tyrosine Phosphatase 1 antibody
Anti-Fap-1 antibody
Anti-Ptp-Bas antibody
Anti-Protein-Tyrosine Phosphatase 1e antibody
Anti-Ptp-E1 antibody
Anti-Hptpe1 antibody
Anti-Protein-Tyrosine Phosphatase Ptpl1 antibody
Anti-PTPN13 antibody
Anti-PNP1 antibody
Anti-PTP1E antibody
Anti-PTPL1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance