| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Tyrosine-protein phosphatase non-receptor type 12 is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PTPN12 |
| Gene ID: |
5782 |
| Uniprot ID: |
PTN12_HUMAN |
| Specificity: |
PTN12 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from part of the human protein |
| Function | Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. Dephosphorylates cellular tyrosine kinases, such as ERBB2 and PTK2B/PYK2, and thereby regulates signaling via ERBB2 and PTK2B/PYK2. Selectively dephosphorylates ERBB2 phosphorylated at 'Tyr-1112', 'Tyr-1196', and/or 'Tyr-1248'. |
| Protein Name | Tyrosine-Protein Phosphatase Non-Receptor Type 12Ptp-PestProtein-Tyrosine Phosphatase G1Ptpg1 |
| Database Links | Reactome: R-HSA-1250196Reactome: R-HSA-182971Reactome: R-HSA-186797Reactome: R-HSA-8863795Reactome: R-HSA-9008059Reactome: R-HSA-9634285 |
| Cellular Localisation | CytoplasmCell JunctionFocal AdhesionCell ProjectionPodosomePartial Translocation To Focal Adhesion Sites May Be Mediated By Interaction With Sorbs2 |
| Alternative Antibody Names | Anti-Tyrosine-Protein Phosphatase Non-Receptor Type 12 antibodyAnti-Ptp-Pest antibodyAnti-Protein-Tyrosine Phosphatase G1 antibodyAnti-Ptpg1 antibodyAnti-PTPN12 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
