| Host: |
Mouse |
| Applications: |
IHC-P |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-Parathyroid Hormone is suitable for use in Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
105G7 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG2a |
| Formulation: |
Tissue culture supernatant with sodium azide |
| Concentration: |
>=12 mg/L |
| Dilution Range: |
IHC-P 1:300 |
| Storage Instruction: |
Store at 2-8°C upon receipt. |
| Immunogen: |
Prokaryotic recombinant protein corresponding to the entire human parathyroid hormone molecule. |
| Background | The parathyroid glands are small, oval, endocrine glands closely associated with the thyroid gland. The parathyroid glands regulate serum calcium and phosphate levels via parathyroid hormone (parathormone). Parathyroid hormone raises serum calcium levels directly, by increasing the rate of osteoclastic reabsorption and promoting breakdown of the bone matrix, and indirectly, by increasing the renal tubular reabsorption of calcium ions and inhibiting the reabsorption of phosphate ions from the glomerular filtrate, and finally, by promoting the absorption of calcium from the small intestine. Parathyroid hormone is the most important regulator of blood calcium levels and is essential to life, whereas calcitonin appears only to provide a complementary mechanism for fine adjustment. Chief cells are the most abundant cells in the parathyroid gland and are responsible for the secretion of parathyroid hormone. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
