| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PTGFR |
| Gene ID: | 5737 |
| Uniprot ID: | PF2R_HUMAN |
| Immunogen Region: | 50-150 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PTGFR (NP_000950.1). |
| Immunogen Sequence: | ILMKAYQRFRQKSKASFLLL ASGLVITDFFGHLINGAIAV FVYASDKEWIRFDQSNVLCS IFGICMVFSGLCPLLLGSVM AIERCIGVTKPIFHSTKITS K |
| Tissue Specificity | Eye. |
| Function | Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum. Isoforms 2 to 7 do not bind PGF2-alpha but are proposed to modulate signaling by participating in variant receptor complexes.heterodimers between isoform 1 and isoform 5 are proposed to be a receptor for prostamides including the synthetic analog bimatoprost. |
| Protein Name | Prostaglandin F2-Alpha ReceptorPgf ReceptorPgf2-Alpha ReceptorProstanoid Fp Receptor |
| Database Links | Reactome: R-HSA-391908Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Prostaglandin F2-Alpha Receptor antibodyAnti-Pgf Receptor antibodyAnti-Pgf2-Alpha Receptor antibodyAnti-Prostanoid Fp Receptor antibodyAnti-PTGFR antibody |
Information sourced from Uniprot.org
