• Immunohistochemistry analysis of PTGES in paraffin-embedded Mouse testis using PTGES Rabbit polyclonal antibody (STJ11100566) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of PTGES in paraffin-embedded Rat testis using PTGES Rabbit polyclonal antibody (STJ11100566) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of various lysates using PTGES Rabbit polyclonal antibody (STJ11100566) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
  • Western blot analysis of lysates from MCF7 cells, using PTGES Rabbit polyclonal antibody (STJ11100566) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-PTGES antibody (1-100) (STJ11100566)

SKU:
STJ11100566

£112.50 - £524.50
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Host: Rabbit
Applications: WB/IHC-P/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
IHC-P:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PTGES
Gene ID: 9536
Uniprot ID: PTGES_HUMAN
Immunogen Region: 1-100
Specificity: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PTGES (NP_004869.1).
Immunogen Sequence: MPAHSLVMSSPALPAFLLCS TLLVIKMYVVAIITGQVRLR KKAFANPEDALRHGGPQYCR SDPDVERCLRAHRNDMETIY PFLFLGFVYSFLGPNPFVAW
Function Terminal enzyme of the cyclooxygenase (COX)-2-mediated prostaglandin E2 (PGE2) biosynthetic pathway. Catalyzes the glutathione-dependent oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) in response to inflammatory stimuli. Plays a key role in inflammation response, fever and pain. Catalyzes also the oxidoreduction of endocannabinoids into prostaglandin glycerol esters and PGG2 into 15-hydroperoxy-PGE2. In addition, displays low glutathione transferase and glutathione-dependent peroxidase activities, toward 1-chloro-2,4-dinitrobenzene and 5-hydroperoxyicosatetraenoic acid (5-HPETE), respectively.
Protein Name Prostaglandin E Synthase
Glutathione Peroxidase Ptges
Glutathione Transferase Ptges
Microsomal Glutathione S-Transferase 1-Like 1
Mgst1-L1
Microsomal Prostaglandin E Synthase 1
Mpges-1
P53-Induced Gene 12 Protein
Database Links Reactome: R-HSA-2162123
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Cytoplasm
Perinuclear Region
Colocalizes With Ptgs1/Cox-1 And Ptgs2/Cox-2 In The Perinuclear Compartment
Alternative Antibody Names Anti-Prostaglandin E Synthase antibody
Anti-Glutathione Peroxidase Ptges antibody
Anti-Glutathione Transferase Ptges antibody
Anti-Microsomal Glutathione S-Transferase 1-Like 1 antibody
Anti-Mgst1-L1 antibody
Anti-Microsomal Prostaglandin E Synthase 1 antibody
Anti-Mpges-1 antibody
Anti-P53-Induced Gene 12 Protein antibody
Anti-PTGES antibody
Anti-MGST1L1 antibody
Anti-MPGES1 antibody
Anti-PGES antibody
Anti-PIG12 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance