| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Prostaglandin E2 receptor EP1 subtype (191-240 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PTGER1 |
| Gene ID: | 5731 |
| Uniprot ID: | PE2R1_HUMAN |
| Immunogen Region: | 191-240 aa |
| Specificity: | EP1 Polyclonal Antibody detects endogenous levels of EP1 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the Internal region of human PTGER1 at the amino acid range 191-240 |
| Post Translational Modifications | Phosphorylated. |
| Function | Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues. |
| Protein Name | Prostaglandin E2 Receptor Ep1 SubtypePge Receptor Ep1 SubtypePge2 Receptor Ep1 SubtypeProstanoid Ep1 Receptor |
| Database Links | Reactome: R-HSA-391908Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Prostaglandin E2 Receptor Ep1 Subtype antibodyAnti-Pge Receptor Ep1 Subtype antibodyAnti-Pge2 Receptor Ep1 Subtype antibodyAnti-Prostanoid Ep1 Receptor antibodyAnti-PTGER1 antibody |
Information sourced from Uniprot.org
