Western blot analysis of lysate from 293 cells, using PTGDR2 Antibody.

Anti-PTGDR2 antibody (161-210 aa) (STJ96770)

SKU:
STJ96770
€60.00 - €315.00
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Prostaglandin D2 receptor 2 (161-210 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PTGDR2
Gene ID: 11251
Uniprot ID: PD2R2_HUMAN
Immunogen Region: 161-210 aa
Specificity: CD294 Polyclonal Antibody detects endogenous levels of CD294 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human PTGDR2 at the amino acid range 161-210
Post Translational Modifications Phosphorylated.
Function Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.
Protein Name Prostaglandin D2 Receptor 2
Chemoattractant Receptor-Homologous Molecule Expressed On Th2 Cells
G-Protein Coupled Receptor 44
Cd Antigen Cd294
Database Links Reactome: R-HSA-391908
Reactome: R-HSA-418594
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Internalized Receptors Colocalized With Rab11a
Alternative Antibody Names Anti-Prostaglandin D2 Receptor 2 antibody
Anti-Chemoattractant Receptor-Homologous Molecule Expressed On Th2 Cells antibody
Anti-G-Protein Coupled Receptor 44 antibody
Anti-Cd Antigen Cd294 antibody
Anti-PTGDR2 antibody
Anti-CRTH2 antibody
Anti-DL1R antibody
Anti-GPR44 antibody

Information sourced from Uniprot.org

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