| Host: | Goat |
| Applications: | Pep-ELISA/WB/IF |
| Reactivity: | Human/Mouse/Rat/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-PTBP2 (Internal) is suitable for use in ELISA, Western Blot and Immunofluorescence research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:1000.WB: Approx 55-60kDa band observed in Mouse Testis lysates and in nuclear lysates of cell line NIH3T3, and approx 55kDa in preliminary testing at Rat testes lysate (calculated MW of 57.6kDa |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | PTBP2 |
| Gene ID: | 58155 |
| Uniprot ID: | PTBP2_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_001287914.1; NP_001287915.1; NP_001287916.1; NP_001287917.1; NP_001287918.1; NP_067013.1 ;Isotype=IgG" |
| Specificity: | This antibody is expected to recognise NP_001287914.1 (isoform 1) , NP_001287915.1 (isoform 2) , NP_001287916.1 (isoform 3) , NP_001287917.1 (isoform 4) , NP_001287918.1 (isoform 5) , and NP_067013.1 (isoform 6). |
| Immunogen Sequence: | SKKFKGEDKMD |
| Function | RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5: Reduced affinity for RNA. |
| Protein Name | Polypyrimidine Tract-Binding Protein 2Neural Polypyrimidine Tract-Binding ProteinNeurally-Enriched Homolog Of PtbPtb-Like Protein |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Polypyrimidine Tract-Binding Protein 2 antibodyAnti-Neural Polypyrimidine Tract-Binding Protein antibodyAnti-Neurally-Enriched Homolog Of Ptb antibodyAnti-Ptb-Like Protein antibodyAnti-PTBP2 antibodyAnti-NPTB antibodyAnti-PTB antibodyAnti-PTBLP antibody |
Information sourced from Uniprot.org