Host: |
Goat |
Applications: |
Pep-ELISA/WB/IF |
Reactivity: |
Human/Mouse/Rat/Cow |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Goat polyclonal antibody anti-PTBP2 (Internal) is suitable for use in ELISA, Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: |
0.5 mg/mL |
Dilution Range: |
IF-Strong expression of the protein seen in the nuclei of A431 cells. 10µg/mlELISA-antibody detection limit dilution 1:1000. |
Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: |
PTBP2 |
Gene ID: |
58155 |
Uniprot ID: |
PTBP2_HUMAN |
Immunogen Region: |
Internal |
Accession Number: |
NP_001287914.1; NP_001287915.1; NP_001287916.1; NP_001287917.1; NP_001287918.1; NP_067013.1 ; |
Specificity: |
This antibody is expected to recognise NP_001287914.1 (isoform 1) , NP_001287915.1 (isoform 2) , NP_001287916.1 (isoform 3) , NP_001287917.1 (isoform 4) , NP_001287918.1 (isoform 5) , and NP_067013.1 (isoform 6). |
Immunogen Sequence: |
SKKFKGEDKMD |
Function | RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5: Reduced affinity for RNA. |
Protein Name | Polypyrimidine Tract-Binding Protein 2Neural Polypyrimidine Tract-Binding ProteinNeurally-Enriched Homolog Of PtbPtb-Like Protein |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Polypyrimidine Tract-Binding Protein 2 antibodyAnti-Neural Polypyrimidine Tract-Binding Protein antibodyAnti-Neurally-Enriched Homolog Of Ptb antibodyAnti-Ptb-Like Protein antibodyAnti-PTBP2 antibodyAnti-NPTB antibodyAnti-PTB antibodyAnti-PTBLP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance