| Short Description : | Rabbit polyclonal anti-Proline/serine-rich coiled-coil protein 1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PSRC1 |
| Gene ID: | 84722 |
| Uniprot ID: | PSRC1_HUMAN |
| Immunogen: | Synthesized peptide derived from human PSRC1 |
| Specificity: | This antibody detects endogenous levels of PSRC1 at Human, Mouse, Rat |
| Post Translational Modifications | Phosphorylated during mitosis. |
| Function | Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase. Plays a role in the regulation of mitotic spindle dynamics. Increases the rate of turnover of microtubules on metaphase spindles, and contributes to the generation of normal tension across sister kinetochores. Recruits KIF2A and ANKRD53 to the mitotic spindle and spindle poles. May participate in p53/TP53-regulated growth suppression. |
| Protein Name | Proline/Serine-Rich Coiled-Coil Protein 1 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonSpindleSpindle PoleDetected At The Mitotic Spindle And Spindle PolesDiffusely Distributed Throughout The Cell During Interphase |
| Alternative Antibody Names | Anti-Proline/Serine-Rich Coiled-Coil Protein 1 antibodyAnti-PSRC1 antibodyAnti-DDA3 antibodyAnti-FP3214 antibody |
Information sourced from Uniprot.org
