| Short Description : | Rabbit monoclonal Phosphoserine Phosphatase (1-225 aa) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S4949RM |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:2000-1:10000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PSPH |
| Gene ID: | 5723 |
| Uniprot ID: | SERB_HUMAN |
| Immunogen Region: | 1-225 aa |
| Immunogen Sequence: | MVSHSELRKLFYSADAVCFD VDSTVIREEGIDELAKICGV EDAVSEMTRRAMGGAVPFKA ALTERLALIQPSREQVQRLI AEQPPHLTPGIRELVSRLQE RNVQVFLISGGFRSIVEHVA SKLNIPATNVFANRLKFYFN GEYAGFDETQPTAESGGKGK VIKLLKEKFHFKKIIMIGDG ATDMEACPPADAFIGFGGNV IRQQVKDNAKWYITDFVELL GELEE |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-225 of human PSPH. (NP_004568.2). |
| Function | Catalyzes the last irreversible step in the biosynthesis of L-serine from carbohydrates, the dephosphorylation of O-phospho-L-serine to L-serine. L-serine can then be used in protein synthesis, to produce other amino acids, in nucleotide metabolism or in glutathione synthesis, or can be racemized to D-serine, a neuromodulator. May also act on O-phospho-D-serine (Probable). |
| Protein Name | Phosphoserine PhosphatasePspPspaseL-3-Phosphoserine PhosphataseO-Phosphoserine Phosphohydrolase |
| Database Links | Reactome: R-HSA-977347 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Phosphoserine Phosphatase antibodyAnti-Psp antibodyAnti-Pspase antibodyAnti-L-3-Phosphoserine Phosphatase antibodyAnti-O-Phosphoserine Phosphohydrolase antibodyAnti-PSPH antibody |
Information sourced from Uniprot.org
