| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PSMB10 |
| Gene ID: | 5699 |
| Uniprot ID: | PSB10_HUMAN |
| Immunogen Region: | 1-273 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-273 of human PSMB10 (NP_002792.1). |
| Immunogen Sequence: | MLKPALEPRGGFSFENCQRN ASLERVLPGLKVPHARKTGT TIAGLVFQDGVILGADTRAT NDSVVADKSCEKIHFIAPKI YCCGAGVAADAEMTTRMVAS KMELHALSTGREPRVATVTR ILRQTLFRYQGHVGASLIVG GVDLTGPQLYGVHPHGSYSR LPFTALGSGQDAALAVLEDR FQPNMTLEAAQGLLVEAVTA GILGDLGSGGNVDACVITKT GAKLLRTLSSPTEPVKRSG |
| Post Translational Modifications | Autocleaved. The resulting N-terminal Thr residue of the mature subunit is responsible for the nucleophile proteolytic activity. |
| Function | The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. |
| Protein Name | Proteasome Subunit Beta Type-10Low Molecular Mass Protein 10Macropain Subunit Mecl-1Multicatalytic Endopeptidase Complex Subunit Mecl-1Proteasome Mecl-1Proteasome Subunit Beta-2i |
| Database Links | Reactome: R-HSA-9907900 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Proteasome Subunit Beta Type-10 antibodyAnti-Low Molecular Mass Protein 10 antibodyAnti-Macropain Subunit Mecl-1 antibodyAnti-Multicatalytic Endopeptidase Complex Subunit Mecl-1 antibodyAnti-Proteasome Mecl-1 antibodyAnti-Proteasome Subunit Beta-2i antibodyAnti-PSMB10 antibodyAnti-LMP10 antibodyAnti-MECL1 antibody |
Information sourced from Uniprot.org
