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Anti-PSIP1 antibody [6E4] (STJ98216)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenPurified recombinant fragment of human LEDGF expressed in E. Coli.
General Information
| Short Description | Mouse monoclonal anti-PC4 and SFRS1-interacting protein for use in WB, IHC, IF and ELISA in Human, Rat and Monkey samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Mouse |
| Reactivity | Human/Rat/Monkey |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 6E4 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB 1:500-1:2000IHC 1:200-1:1000IF 1:200-1:1000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PSIP1 |
| Gene ID | 11168 |
| Uniprot ID | PSIP1_HUMAN |
| Immunogen | Purified recombinant fragment of human LEDGF expressed in E. Coli. |
| Specificity | LEDGF Monoclonal Antibody detects endogenous levels of LEDGF protein. |
Additional Info
| Post Translational Modifications | Citrullinated by PADI4. |
| Function | Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration. |
| Protein Name | Pc4 And Sfrs1-Interacting ProteinCll-Associated Antigen Kw-7Dense Fine Speckles 70 Kda ProteinDfs 70Lens Epithelium-Derived Growth FactorTranscriptional Coactivator P75/P52 |
| Database Links | Reactome: R-HSA-162592Reactome: R-HSA-164843Reactome: R-HSA-175567Reactome: R-HSA-177539Reactome: R-HSA-180689Reactome: R-HSA-180910Reactome: R-HSA-9772755 |
| Cellular Localisation | NucleusRemains Chromatin-Associated Throughout The Cell Cycle |
| Alternative Antibody Names | Anti-Pc4 And Sfrs1-Interacting Protein antibodyAnti-Cll-Associated Antigen Kw-7 antibodyAnti-Dense Fine Speckles 70 Kda Protein antibodyAnti-Dfs 70 antibodyAnti-Lens Epithelium-Derived Growth Factor antibodyAnti-Transcriptional Coactivator P75/P52 antibodyAnti-PSIP1 antibodyAnti-DFS70 antibodyAnti-LEDGF antibodyAnti-PSIP2 antibody |
Information sourced from Uniprot.org