| Host: | Mouse |
| Applications: | ELISA/FC/WB/IF/IHC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-PSA is suitable for use in ELISA, Flow Cytometry, Western Blot, Immunofluorescence and Immunohistochemistry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | EBS-T-231 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1k |
| Formulation: | PBS with 0.02% Sodium Azide. |
| Purification: | Affinity purified from tissue culture. |
| Concentration: | Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
| Dilution Range: | ELISA (solid phase: 0, 1-100 µg/ml; tracer: 0, 001-100 µg/ml for 30 min at RT). Flow Cytometry (0, 5-1, 0 µg/million cells in 0, 1 ml). Immunoblotting (1 µg/ml for 2h at RT). Immunofluorescence (0, 5-1, 0 µg/ml). Immunohistology (formalin-fixed: 1-2 |
| Storage Instruction: | Store for up to 1 year at 2-8°C upon receipt. |
| Gene Symbol: | NPEPPS |
| Gene ID: | 9520 |
| Uniprot ID: | PSA_HUMAN |
| Immunogen: | A BALB/c mouse was immunized with a p30 enriched preparation of human sperm plasma. Fusion partner: P3-X63-Ag8.653. |
| Function | Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway for MHC class I molecules. Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors. Digests the poly-Q peptides found in many cellular proteins. Digests tau from normal brain more efficiently than tau from Alzheimer disease brain. |
| Protein Name | Puromycin-Sensitive AminopeptidasePsaCytosol Alanyl AminopeptidaseAap-S |
| Database Links | Reactome: R-HSA-983168 |
| Cellular Localisation | CytoplasmCytosolNucleus |
| Alternative Antibody Names | Anti-Puromycin-Sensitive Aminopeptidase antibodyAnti-Psa antibodyAnti-Cytosol Alanyl Aminopeptidase antibodyAnti-Aap-S antibodyAnti-NPEPPS antibodyAnti-PSA antibody |
Information sourced from Uniprot.org