| Tissue Specificity | Found in prostate, liver, salivary gland, kidney, lung, pancreas, colon, bronchus and renal proximal tubular cells. In the prostate gland it may be synthesized in epithelial cells, secreted into the ducts, and excreted into the seminal fluid. |
| Function | Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G). |
| Protein Name | ProstasinChannel-Activating Protease 1Cap1Serine Protease 8 Cleaved Into - Prostasin Light Chain - Prostasin Heavy Chain |
| Database Links | Reactome: R-HSA-6809371 |
| Cellular Localisation | Prostasin: Cell MembraneSingle-Pass Membrane ProteinProstasin Light Chain: SecretedExtracellular SpaceFound In The Seminal FluidSecreted After Cleavage Of Its C-TerminusProstasin Heavy Chain: Secreted |
| Alternative Antibody Names | Anti-Prostasin antibodyAnti-Channel-Activating Protease 1 antibodyAnti-Cap1 antibodyAnti-Serine Protease 8 Cleaved Into - Prostasin Light Chain - Prostasin Heavy Chain antibodyAnti-PRSS8 antibody |
Information sourced from Uniprot.org
