| Tissue Specificity | Expressed in Paneth cells, at the base of small intestinal crypts. |
| Post Translational Modifications | Sulfated on tyrosine. Sulfation at Tyr-154 increases selectivity towards basic versus apolar residues at the P2' position of inhibitors that bind in a substrate-like fashion. Although the increase in selectivity is relatively small, it may facilitate digestion of a broader range of dietary proteins. |
| Function | In the ileum, may be involved in defensin processing, including DEFA5. |
| Protein Name | Trypsin-2Anionic TrypsinogenSerine Protease 2Trypsin Ii |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1462054Reactome: R-HSA-1592389Reactome: R-HSA-6798695Reactome: R-HSA-6803157 |
| Cellular Localisation | SecretedExtracellular Space |
| Alternative Antibody Names | Anti-Trypsin-2 antibodyAnti-Anionic Trypsinogen antibodyAnti-Serine Protease 2 antibodyAnti-Trypsin Ii antibodyAnti-PRSS2 antibodyAnti-TRY2 antibodyAnti-TRYP2 antibody |
Information sourced from Uniprot.org
