Name: Anti-PRPF8 antibody (1-100) (STJ27847)
SKU: STJ27847
Availability: InStock

Anti-PRPF8 antibody (1-100) (STJ27847)

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STJ27847

$151.88 - $708.08

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Host:	Rabbit
Applications:	WB/IHC-P/IF/ICC/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality :	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification:	Affinity purification
Concentration:	Lot specific
Dilution Range:	WB:1:500-1:1000 IHC-P:1:50-1:200 IF/ICC:1:50-1:100 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	PRPF8
Gene ID:	10594
Uniprot ID:	PRP8_HUMAN
Immunogen Region:	1-100
Specificity:	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PRPF8 (NP_006436.3).
Immunogen Sequence:	MAGVFPYRGPGNPVPGPLAP LPDYMSEEKLQEKARKWQQL QAKRYAEKRKFGFVDAQKED MPPEHVRKIIRDHGDMTNRK FRHDKRVYLGALKYMPHAVL

Tissue Specificity	Widely expressed.
Function	Plays a role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes, both of the predominant U2-type spliceosome and the minor U12-type spliceosome. Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. Functions as a scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both the 5' and the 3' splice site.
Protein Name	Pre-Mrna-Processing-Splicing Factor 8 220 Kda U5 Snrnp-Specific Protein Prp8 Homolog Splicing Factor Prp8 P220
Database Links	Reactome: R-HSA-72163 Reactome: R-HSA-72165
Cellular Localisation	Nucleus Nucleus Speckle
Alternative Antibody Names	Anti-Pre-Mrna-Processing-Splicing Factor 8 antibody Anti-220 Kda U5 Snrnp-Specific Protein antibody Anti-Prp8 Homolog antibody Anti-Splicing Factor Prp8 antibody Anti-P220 antibody Anti-PRPF8 antibody Anti-PRPC8 antibody

Information sourced from Uniprot.org

Model	Name	Host	Clonality	Reactivity	Application
STJ11102107	Anti-PRPF8 antibody (2200-2335) [S7MR] (STJ11102107)	Rabbit	Monoclonal	Human/Mouse/Rat	WB/IHC-P/IF/ICC/ELISA
STJ191202	Anti-PRPF8 antibody (160-240 aa) (STJ191202)	Rabbit	Polyclonal	Human/Mouse	IHC/IF
STJ11103302	Anti-NKX6-1 antibody (1-100) (STJ11103302)	Rabbit	Polyclonal	Human/Mouse/Rat	WB/IHC-P/ELISA
STJ501756	Anti-MINPP1 antibody (1-100) (STJ501756)	Rabbit	Polyclonal	Human/Mouse/Rat	ELISA/IP/WB
STJ114330	Anti-KTN1 antibody (1-100) (STJ114330)	Rabbit	Polyclonal	Human/Mouse/Rat	WB/ELISA

Anti-PRPF8 antibody (1-100) (STJ27847)