Anti-PRPF6 antibody (747-796 aa) (STJ95230)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human PRPF6 at the amino acid range 747-796
General Information
| Short Description | Rabbit polyclonal anti-Pre-mRNA-processing factor 6 (747-796 aa) for use in IHC, IF, WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PRPF6 |
| Gene ID | 24148 |
| Uniprot ID | PRP6_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human PRPF6 at the amino acid range 747-796 |
| Immunogen Region | 747-796 aa |
| Specificity | PRP6 Polyclonal Antibody detects endogenous levels of PRP6 protein. |
Additional Info
| Post Translational Modifications | Phosphorylated by PRP4K during spliceosome assembly. |
| Function | Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation. |
| Protein Name | Pre-Mrna-Processing Factor 6Androgen Receptor N-Terminal Domain-Transactivating Protein 1Ant-1Prp6 HomologU5 Snrnp-Associated 102 Kda ProteinU5-102 Kda Protein |
| Database Links | Reactome: R-HSA-72163Reactome: R-HSA-72165 |
| Cellular Localisation | NucleusNucleoplasmNucleus SpeckleLocalized In Splicing Speckles |
| Alternative Antibody Names | Anti-Pre-Mrna-Processing Factor 6 antibodyAnti-Androgen Receptor N-Terminal Domain-Transactivating Protein 1 antibodyAnti-Ant-1 antibodyAnti-Prp6 Homolog antibodyAnti-U5 Snrnp-Associated 102 Kda Protein antibodyAnti-U5-102 Kda Protein antibodyAnti-PRPF6 antibodyAnti-C20orf14 antibody |
Information sourced from Uniprot.org