| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PRPF4 |
| Gene ID: | 9128 |
| Uniprot ID: | PRP4_HUMAN |
| Immunogen Region: | 1-260 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PRPF4 (NP_004688.2). |
| Immunogen Sequence: | MASSRASSTQATKTKAPDDL VAPVVKKPHIYYGSLEEKER ERLAKGESGILGKDGLKAGI EAGNINITSGEVFEIEEHIS ERQAEVLAEFERRKRARQIN VSTDDSEVKACLRALGEPIT LFGEGPAERRERLRNILSVV GTDALKKTKKDDEKSKKSKE EYQQTWYHEGPNSLKVARLW IANYSLPRAMKRLEEARLHK EIPETTRTSQMQELHKSLRS LNNFCSQIGDDRPISYCHF |
| Function | Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). |
| Protein Name | U4/U6 Small Nuclear Ribonucleoprotein Prp4Prp4 HomologHprp4U4/U6 Snrnp 60 Kda ProteinWd Splicing Factor Prp4 |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | NucleusNucleus Speckle |
| Alternative Antibody Names | Anti-U4/U6 Small Nuclear Ribonucleoprotein Prp4 antibodyAnti-Prp4 Homolog antibodyAnti-Hprp4 antibodyAnti-U4/U6 Snrnp 60 Kda Protein antibodyAnti-Wd Splicing Factor Prp4 antibodyAnti-PRPF4 antibodyAnti-PRP4 antibody |
Information sourced from Uniprot.org