| Host: | Rabbit |
| Applications: | WB/ELISA/IHC |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-U4/U6 small nuclear ribonucleoprotein Prp31 (331-380 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 IHC-P 1:50-300 ELISA 2000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PRPF31 |
| Gene ID: | 26121 |
| Uniprot ID: | PRP31_HUMAN |
| Immunogen Region: | 331-380 aa |
| Specificity: | PRPF31 Polyclonal Antibody detects endogenous levels of PRPF31 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human PRP31 at the amino acid range 331-380 |
| Post Translational Modifications | Phosphorylated by PRP4K during spliceosome assembly. |
| Function | Involved in pre-mRNA splicing as component of the spliceosome. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. |
| Protein Name | U4/U6 Small Nuclear Ribonucleoprotein Prp31 Pre-Mrna-Processing Factor 31 Serologically Defined Breast Cancer Antigen Ny-Br-99 U4/U6 Snrnp 61 Kda Protein Protein 61k Hprp31 |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | Nucleus Nucleus Speckle Cajal Body Predominantly Found In Speckles And In Cajal Bodies |
| Alternative Antibody Names | Anti-U4/U6 Small Nuclear Ribonucleoprotein Prp31 antibody Anti-Pre-Mrna-Processing Factor 31 antibody Anti-Serologically Defined Breast Cancer Antigen Ny-Br-99 antibody Anti-U4/U6 Snrnp 61 Kda Protein antibody Anti-Protein 61k antibody Anti-Hprp31 antibody Anti-PRPF31 antibody Anti-PRP31 antibody |
Information sourced from Uniprot.org