Anti-PROCR antibody [ZN200] (STJA0033370)

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STJA0033370
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Short Description :Mouse monoclonal anti-PROCR for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC-P
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :ZN200
Isotype:IgG2a
Conjugation:Unconjugated
Concentration:0.5-1.0 mg/mL
Purification:Affinity Chromatography
Dilution Range:IHC 1:50-1:100
Formulation:PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:PROCR
Gene ID:10544
Uniprot ID:EPCR_HUMAN
Immunogen:Human recombinant protein fragment of human PROCR (NP_006395) produced in HEK293T cell.
Tissue Specificity Expressed strongly in the endothelial cells of arteries and veins in heart and lung, less intensely in capillaries in the lung and skin, and not at all in the endothelium of small vessels of the liver and kidney.
Post Translational Modifications N-glycosylated. A soluble form exists.probably released by a metalloprotease. Seems to have the same activity as the membrane-bound form.
Function Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex.plays a role in the protein C pathway controlling blood coagulation.
Protein Name Endothelial Protein C Receptor
Activated Protein C Receptor
Apc Receptor
Endothelial Cell Protein C Receptor
Cd Antigen Cd201
Database Links Reactome: R-HSA-140875
Reactome: R-HSA-202733
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Endothelial Protein C Receptor antibody
Anti-Activated Protein C Receptor antibody
Anti-Apc Receptor antibody
Anti-Endothelial Cell Protein C Receptor antibody
Anti-Cd Antigen Cd201 antibody
Anti-PROCR antibody
Anti-EPCR antibody

Information sourced from Uniprot.org