Anti-PRMT8 antibody (200-380) (STJ11105071)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal Protein Arginine N-Methyltransferase 8 (200-380) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PRMT8 |
| Gene ID | 56341 |
| Uniprot ID | ANM8_HUMAN |
| Immunogen Region | 200-380 |
| Immunogen Sequence | VIFARDKWLKPGGLMFPDRA ALYVVAIEDRQYKDFKIHWW ENVYGFDMTCIRDVAMKEPL VDIVDPKQVVTNACLIKEVD IYTVKTEELSFTSAFCLQIQ RNDYVHALVTYFNIEFTKCH KKMGFSTAPDAPYTHWKQTV FYLEDYLTVRRGEEIYGTIS MKPNAKNVRDLDFTVDLDFK G |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 200-380 of human PRMT8 (NP_062828.3). |
Additional Info
| Tissue Specificity | Brain-specific. |
| Function | S-adenosyl-L-methionine-dependent and membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA) in proteins such as NIFK, myelin basic protein, histone H4, H2A and H2A/H2B dimer. Able to mono- and dimethylate EWS protein.however its precise role toward EWS remains unclear as it still interacts with fully methylated EWS. |
| Protein Name | Protein Arginine N-Methyltransferase 8Heterogeneous Nuclear Ribonucleoprotein Methyltransferase-Like Protein 4 |
| Database Links | |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic Side |
| Alternative Antibody Names | Anti-Protein Arginine N-Methyltransferase 8 antibodyAnti-Heterogeneous Nuclear Ribonucleoprotein Methyltransferase-Like Protein 4 antibodyAnti-PRMT8 antibodyAnti-HRMT1L3 antibodyAnti-HRMT1L4 antibody |
Information sourced from Uniprot.org