| Short Description : | Human monoclonal Prolactin Receptor antibody for use in FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | FC |
| Host: | Human |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | h16f |
| Isotype: | IgG1k |
| Conjugation: | Unconjugated |
| Concentration: | 1.9 mg/ml |
| Purification: | Protein A/G purified from cell culture supernatant. |
| Formulation: | 0.01M PBS, pH 7.4. |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Gene Symbol: | PRLR |
| Gene ID: | 5618 |
| Uniprot ID: | PRLR_HUMAN |
| Function | This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling. |
| Protein Name | Prolactin ReceptorPrl-R |
| Database Links | Reactome: R-HSA-1170546Reactome: R-HSA-982772 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinIsoform 7: Secreted |
| Alternative Antibody Names | Anti-Prolactin Receptor antibodyAnti-Prl-R antibodyAnti-PRLR antibody |
Information sourced from Uniprot.org