Anti-PRKX antibody (251-300 aa) (STJ95224)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human PRKX at the amino acid range 251-300
General Information
| Short Description | Rabbit polyclonal anti-cAMP-dependent protein kinase catalytic subunit PRKX (251-300 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PRKX |
| Gene ID | 5613 |
| Uniprot ID | PRKX_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human PRKX at the amino acid range 251-300 |
| Immunogen Region | 251-300 aa |
| Specificity | PRKX Polyclonal Antibody detects endogenous levels of PRKX protein. |
Additional Info
| Post Translational Modifications | Phosphorylated.autophosphorylates in vitro. |
| Function | Serine/threonine protein kinase regulated by and mediating cAMP signaling in cells. Acts through phosphorylation of downstream targets that may include CREB, SMAD6 and PKD1 and has multiple functions in cellular differentiation and epithelial morphogenesis. Regulates myeloid cell differentiation through SMAD6 phosphorylation. Involved in nephrogenesis by stimulating renal epithelial cell migration and tubulogenesis. Also involved in angiogenesis through stimulation of endothelial cell proliferation, migration and vascular-like structure formation. |
| Protein Name | Camp-Dependent Protein Kinase Catalytic Subunit PrkxPrkxProtein Kinase XProtein Kinase X-LinkedSerine/Threonine-Protein Kinase PrkxProtein Kinase Pkx1 |
| Database Links | Reactome: R-HSA-111931Reactome: R-HSA-442720Reactome: R-HSA-9660821Reactome: R-HSA-9664323 |
| Cellular Localisation | CytoplasmNucleusCamp Induces Nuclear Translocation |
| Alternative Antibody Names | Anti-Camp-Dependent Protein Kinase Catalytic Subunit Prkx antibodyAnti-Prkx antibodyAnti-Protein Kinase X antibodyAnti-Protein Kinase X-Linked antibodyAnti-Serine/Threonine-Protein Kinase Prkx antibodyAnti-Protein Kinase Pkx1 antibodyAnti-PRKX antibodyAnti-PKX1 antibody |
Information sourced from Uniprot.org