• Western blot analysis of lysates from MCF-7 cells, using PRKX Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of the lysates from HepG2 cells using PRKX antibody.
  • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using PRKX Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-PRKX antibody (251-300 aa) (STJ95224)

SKU:
STJ95224

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-cAMP-dependent protein kinase catalytic subunit PRKX (251-300 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PRKX
Gene ID: 5613
Uniprot ID: PRKX_HUMAN
Immunogen Region: 251-300 aa
Specificity: PRKX Polyclonal Antibody detects endogenous levels of PRKX protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human PRKX at the amino acid range 251-300
Post Translational Modifications Phosphorylated.autophosphorylates in vitro.
Function Serine/threonine protein kinase regulated by and mediating cAMP signaling in cells. Acts through phosphorylation of downstream targets that may include CREB, SMAD6 and PKD1 and has multiple functions in cellular differentiation and epithelial morphogenesis. Regulates myeloid cell differentiation through SMAD6 phosphorylation. Involved in nephrogenesis by stimulating renal epithelial cell migration and tubulogenesis. Also involved in angiogenesis through stimulation of endothelial cell proliferation, migration and vascular-like structure formation.
Protein Name Camp-Dependent Protein Kinase Catalytic Subunit Prkx
Prkx
Protein Kinase X
Protein Kinase X-Linked
Serine/Threonine-Protein Kinase Prkx
Protein Kinase Pkx1
Database Links Reactome: R-HSA-111931
Reactome: R-HSA-442720
Reactome: R-HSA-9660821
Reactome: R-HSA-9664323
Cellular Localisation Cytoplasm
Nucleus
Camp Induces Nuclear Translocation
Alternative Antibody Names Anti-Camp-Dependent Protein Kinase Catalytic Subunit Prkx antibody
Anti-Prkx antibody
Anti-Protein Kinase X antibody
Anti-Protein Kinase X-Linked antibody
Anti-Serine/Threonine-Protein Kinase Prkx antibody
Anti-Protein Kinase Pkx1 antibody
Anti-PRKX antibody
Anti-PKX1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance