Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-PRKCSH (130-275) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
PRKCSH |
Gene ID: |
5589 |
Uniprot ID: |
GLU2B_HUMAN |
Immunogen Region: |
130-275 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 130-275 of human PRKCSH (P14314). |
Immunogen Sequence: |
MAEVTREGFRLKKILIEDWK KAREEKQKKLIELQAGKKSL EDQVEMLRTVKEEAEKPERE AKEQHQKLWEEQLAAAKAQQ EQELAADAFKELDDDMDGTV SVTELQTHPELDTDGDGALS EAEAQALLSGDTQTDATSFY DRVWAA |
Function | Regulatory subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins. Required for efficient PKD1/Polycystin-1 biogenesis and trafficking to the plasma membrane of the primary cilia. |
Protein Name | Glucosidase 2 Subunit Beta80k-H ProteinGlucosidase Ii Subunit BetaProtein Kinase C Substrate 60.1 Kda Protein Heavy ChainPkcsh |
Database Links | Reactome: R-HSA-381426Reactome: R-HSA-532668Reactome: R-HSA-879415Reactome: R-HSA-8957275Reactome: R-HSA-901042Reactome: R-HSA-9683686Reactome: R-HSA-9694548 |
Cellular Localisation | Endoplasmic Reticulum |
Alternative Antibody Names | Anti-Glucosidase 2 Subunit Beta antibodyAnti-80k-H Protein antibodyAnti-Glucosidase Ii Subunit Beta antibodyAnti-Protein Kinase C Substrate 60.1 Kda Protein Heavy Chain antibodyAnti-Pkcsh antibodyAnti-PRKCSH antibodyAnti-G19P1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance