| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PRKCDBP (75-160) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CAVIN3 |
| Gene ID: |
112464 |
| Uniprot ID: |
CAVN3_HUMAN |
| Immunogen Region: |
75-160 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 75-160 of human PRKCDBP (NP_659477.2). |
| Immunogen Sequence: |
SNTLAQLLAKAERVSSHANA AQERAVRRAAQVQRLEANHG LLVARGKLHVLLFKEEGEVP ASAFQKAPEPLGPADQSELG PEQLEA |
| Tissue Specificity | Skeletal muscle, liver, stomach, lung, kidney and heart (at protein level). Strongly expressed in mammary and epithelial cells. |
| Post Translational Modifications | In vitro, phosphorylated by PRKCD. |
| Function | Regulates the traffic and/or budding of caveolae. Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in smooth muscle but not in the lung and heart endothelial cells. Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by promoting the rapid release of caveolae from the cell surface. Plays a role in the regulation of the circadian clock. Modulates the period length and phase of circadian gene expression and also regulates expression and interaction of the core clock components PER1/2 and CRY1/2. |
| Protein Name | Caveolae-Associated Protein 3Cavin-3Protein Kinase C Delta-Binding ProteinSerum Deprivation Response Factor-Related Gene Product That Binds To C-KinaseHsrbc |
| Cellular Localisation | CytoplasmMembraneCaveolaCytosolLocalizes In The Caveolae In A Caveolin-Dependent Manner |
| Alternative Antibody Names | Anti-Caveolae-Associated Protein 3 antibodyAnti-Cavin-3 antibodyAnti-Protein Kinase C Delta-Binding Protein antibodyAnti-Serum Deprivation Response Factor-Related Gene Product That Binds To C-Kinase antibodyAnti-Hsrbc antibodyAnti-CAVIN3 antibodyAnti-PRKCDBP antibodyAnti-SRBC antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
