Anti-PREX1 antibody (340-420 aa) (STJ191145)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 340-420
General Information
| Short Description | Rabbit polyclonal anti-Phosphatidylinositol 3, 4, 5-trisphosphate-dependent Rac exchanger 1 protein-dependent Rac exchanger 1 (340-420 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and relat |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PREX1 |
| Gene ID | 57580 |
| Uniprot ID | PREX1_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 340-420 |
| Immunogen Region | 340-420 aa |
| Specificity | PREX1 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils. |
| Protein Name | Phosphatidylinositol 3 -4 -5-Trisphosphate-Dependent Rac Exchanger 1 ProteinP-Rex1Ptdins(3 -4 -5-Dependent Rac Exchanger 1 |
| Database Links | Reactome: R-HSA-193648Reactome: R-HSA-416482Reactome: R-HSA-8980692Reactome: R-HSA-9013026Reactome: R-HSA-9013106Reactome: R-HSA-9013148Reactome: R-HSA-9013149Reactome: R-HSA-9013404Reactome: R-HSA-9013406Reactome: R-HSA-9013408Reactome: R-HSA-9013409Reactome: R-HSA-9013423 |
| Cellular Localisation | CytoplasmCytosolCell MembraneMainly CytosolicSome Amount Is Apparently Associated To The Plasma Membrane |
| Alternative Antibody Names | Anti-Phosphatidylinositol 3 -4 -5-Trisphosphate-Dependent Rac Exchanger 1 Protein antibodyAnti-P-Rex1 antibodyAnti-Ptdins(3 -4 -5-Dependent Rac Exchanger 1 antibodyAnti-PREX1 antibodyAnti-KIAA1415 antibody |
Information sourced from Uniprot.org