| Short Description : | Rabbit polyclonal anti-PR domain zinc finger protein 5 (31-81 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PRDM5 |
| Gene ID: | 11107 |
| Uniprot ID: | PRDM5_HUMAN |
| Immunogen: | Synthesized peptide derived from the human PRDM5 at the amino acid range 31-81 |
| Immunogen Region: | 31-81 aa |
| Specificity: | This antibody detects endogenous levels of PRDM5 at Human/Mouse |
| Function | Sequence-specific DNA-binding transcription factor. Represses transcription at least in part by recruitment of the histone methyltransferase EHMT2/G9A and histone deacetylases such as HDAC1. Regulates hematopoiesis-associated protein-coding and microRNA (miRNA) genes. May regulate the expression of proteins involved in extracellular matrix development and maintenance, including fibrillar collagens, such as COL4A1 and COL11A1, connective tissue components, such as HAPLN1, and molecules regulating cell migration and adhesion, including EDIL3 and TGFB2. May cause G2/M arrest and apoptosis in cancer cells. |
| Protein Name | Pr Domain Zinc Finger Protein 5Pr Domain-Containing Protein 5 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Pr Domain Zinc Finger Protein 5 antibodyAnti-Pr Domain-Containing Protein 5 antibodyAnti-PRDM5 antibodyAnti-PFM2 antibody |
Information sourced from Uniprot.org
