| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PRCP |
| Gene ID: | 5547 |
| Uniprot ID: | PCP_HUMAN |
| Immunogen Region: | 407-496 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 407-496 of human PRCP (NP_005031.1). |
| Immunogen Sequence: | ITTMYGGKNISSHTNIVFSN GELDPWSGGGVTKDITDTLV AVTISEGAHHLDLRTKNALD PMSVLLARSLEVRHMKNWIR DFYDSAGKQH |
| Tissue Specificity | Highest levels in placenta, lung and liver. Also present in heart, brain, pancreas and kidney. |
| Function | Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH. |
| Protein Name | Lysosomal Pro-X CarboxypeptidaseAngiotensinase CLysosomal Carboxypeptidase CProline CarboxypeptidaseProlylcarboxypeptidasePrcp |
| Database Links | Reactome: R-HSA-140837Reactome: R-HSA-6798695 |
| Cellular Localisation | Lysosome |
| Alternative Antibody Names | Anti-Lysosomal Pro-X Carboxypeptidase antibodyAnti-Angiotensinase C antibodyAnti-Lysosomal Carboxypeptidase C antibodyAnti-Proline Carboxypeptidase antibodyAnti-Prolylcarboxypeptidase antibodyAnti-Prcp antibodyAnti-PRCP antibodyAnti-PCP antibody |
Information sourced from Uniprot.org
