| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PRCP (407-496) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PRCP |
| Gene ID: |
5547 |
| Uniprot ID: |
PCP_HUMAN |
| Immunogen Region: |
407-496 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 407-496 of human PRCP (NP_005031.1). |
| Immunogen Sequence: |
ITTMYGGKNISSHTNIVFSN GELDPWSGGGVTKDITDTLV AVTISEGAHHLDLRTKNALD PMSVLLARSLEVRHMKNWIR DFYDSAGKQH |
| Tissue Specificity | Highest levels in placenta, lung and liver. Also present in heart, brain, pancreas and kidney. |
| Function | Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH. |
| Protein Name | Lysosomal Pro-X CarboxypeptidaseAngiotensinase CLysosomal Carboxypeptidase CProline CarboxypeptidaseProlylcarboxypeptidasePrcp |
| Database Links | Reactome: R-HSA-140837Reactome: R-HSA-6798695 |
| Cellular Localisation | Lysosome |
| Alternative Antibody Names | Anti-Lysosomal Pro-X Carboxypeptidase antibodyAnti-Angiotensinase C antibodyAnti-Lysosomal Carboxypeptidase C antibodyAnti-Proline Carboxypeptidase antibodyAnti-Prolylcarboxypeptidase antibodyAnti-Prcp antibodyAnti-PRCP antibodyAnti-PCP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
