| Host: | Goat |
| Applications: | Pep-ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-Praja-1/RNF70 (285-298) is suitable for use in ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:4000.WB: Preliminary experiments gave an approx 30kDa band in Human Brain and Mouse Brain lysates after 1µg/ml antibody staining. Please note that currently we cannot find an explanation in the |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | PJA1 |
| Gene ID: | 64219 |
| Uniprot ID: | PJA1_HUMAN |
| Immunogen Region: | 285-298 |
| Accession Number: | NP_660095.1; NP_001027568.1; NP_071763.2 |
| Specificity: | This antibody is expected to recognize all reported isoforms (NP_660095.1; NP_001027568.1; NP_071763.2). |
| Immunogen Sequence: | HSTSRWRDTANDNE |
| Post Translational Modifications | Substrate for E2-dependent ubiquitination. |
| Function | Has E2-dependent E3 ubiquitin-protein ligase activity. Ubiquitinates MAGED1 antigen leading to its subsequent degradation by proteasome. May be involved in protein sorting. |
| Protein Name | E3 Ubiquitin-Protein Ligase Praja-1Praja1Ring Finger Protein 70Ring-Type E3 Ubiquitin Transferase Praja-1 |
| Database Links | Reactome: R-HSA-983168 |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Praja-1 antibodyAnti-Praja1 antibodyAnti-Ring Finger Protein 70 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Praja-1 antibodyAnti-PJA1 antibodyAnti-RNF70 antibody |
Information sourced from Uniprot.org