Anti-PPT1 antibody (28-306) (STJ116969)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PPT1 (28-306) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PPT1 |
| Gene ID | 5538 |
| Uniprot ID | PPT1_HUMAN |
| Immunogen Region | 28-306 |
| Immunogen Sequence | DPPAPLPLVIWHGMGDSCCN PLSMGAIKKMVEKKIPGIYV LSLEIGKTLMEDVENSFFLN VNSQVTTVCQALAKDPKLQQ GYNAMGFSQGGQFLRAVAQR CPSPPMINLISVGGQHQGVF GLPRCPGESSHICDFIRKTL NAGAYSKVVQERLVQAEYWH DPIKEDVYRNHSIFLADINQ ERGINESYKKNLMALKKFVM VKFLNDSIVDPVDSEWFGFY RSGQAKETIPLQETSLYTQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 28-306 of human PPT1 (NP_000301.1). |
Additional Info
| Post Translational Modifications | Glycosylated. |
| Function | Has thioesterase activity against fatty acid thioesters with 14 -18 carbons, including palmitoyl-CoA, S-palmitoyl-N-acetylcysteamine, and palmitoylated proteins. In contrast to PPT2, PPT1 can hydrolyze palmitoylated proteins and palmitoylcysteine. |
| Protein Name | Palmitoyl-Protein Thioesterase 1Ppt-1Palmitoyl-Protein Hydrolase 1 |
| Database Links | Reactome: R-HSA-75105 |
| Cellular Localisation | LysosomeSecretedGolgi ApparatusEndoplasmic Reticulum |
| Alternative Antibody Names | Anti-Palmitoyl-Protein Thioesterase 1 antibodyAnti-Ppt-1 antibodyAnti-Palmitoyl-Protein Hydrolase 1 antibodyAnti-PPT1 antibodyAnti-CLN1 antibodyAnti-PPT antibody |
Information sourced from Uniprot.org