Anti-PPP4R1 antibody (324-647) (STJ110659)

SKU:
STJ110659
£112.50 - £524.50
Free Shipping
Processing The item has been added

Host: Rabbit
Applications: WB/IP/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cells
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PPP4R1
Gene ID: 9989
Uniprot ID: PP4R1_HUMAN
Immunogen Region: 324-647
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 324-647 of human PPP4R1 (NP_001035847.1).
Immunogen Sequence: NPSSSGQYFKEESKSSEEMS VENKNRTRDQEAPEDVQVRP EDTPSDLSVSNSSVILENTM EDHAAEASGKPLGEISVPLD SSLLCTLSSESHQEAASNEN DKKPGNYKSMLRPEVGTTSQ DSALLDQELYNSFHFWRTPL PEIDLDIELEQNSGGKPSPE GPEEESEGPVPSSPNITMAT RKELEEMIENLEPHIDDPDV KAQVEVLSAALRASSLDAHE ETISIEKRSDLQDELDINE
Tissue Specificity Widely expressed with high expression in cultured mesangial cells. Isoform 1 and isoform 2 are expressed in renal tissues.
Function Regulatory subunit of serine/threonine-protein phosphatase 4. May play a role in regulation of cell division in renal glomeruli. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. Plays a role in the inhibition of TNF-induced NF-kappa-B activation by regulating the dephosphorylation of TRAF2. (Microbial infection) Participates in merkel polyomavirus-mediated inhibition of NF-kappa-B by bridging viral small tumor antigen with NEMO.
Protein Name Serine/Threonine-Protein Phosphatase 4 Regulatory Subunit 1
Alternative Antibody Names Anti-Serine/Threonine-Protein Phosphatase 4 Regulatory Subunit 1 antibody
Anti-PPP4R1 antibody
Anti-MEG1 antibody
Anti-PP4R1 antibody

Information sourced from Uniprot.org