| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:100-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PPP2R5D |
| Gene ID: | 5528 |
| Uniprot ID: | 2A5D_HUMAN |
| Immunogen Region: | 450-550 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 450-550 of human PP2A-B56 Delta/PR61 Delta/PP2A-B56 Delta/PR61 Delta/PPP2R5D (NP_006236.1). |
| Immunogen Sequence: | LYRNSKSHWNKTIHGLIYNA LKLFMEMNQKLFDDCTQQYK AEKQKGRFRMKEREEMWQKI EELARLNPQYPMFRAPPPLP PVYSMETETPTAEDIQLLKR T |
| Tissue Specificity | Isoform Delta-2 is widely expressed. Isoform Delta-1 is highly expressed in brain. |
| Function | The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. |
| Protein Name | Serine/Threonine-Protein Phosphatase 2a 56 Kda Regulatory Subunit Delta IsoformPp2a B Subunit Isoform B'-DeltaPp2a B Subunit Isoform B56-DeltaPp2a B Subunit Isoform Pr61-DeltaPp2a B Subunit Isoform R5-Delta |
| Database Links | Reactome: R-HSA-141444Reactome: R-HSA-163685Reactome: R-HSA-163767Reactome: R-HSA-180024Reactome: R-HSA-195253Reactome: R-HSA-196299Reactome: R-HSA-198753Reactome: R-HSA-202670Reactome: R-HSA-2467813Reactome: R-HSA-2500257Reactome: R-HSA-389513Reactome: R-HSA-432142Reactome: R-HSA-4641262Reactome: R-HSA-5339716Reactome: R-HSA-5358747Reactome: R-HSA-5358749Reactome: R-HSA-5358751Reactome: R-HSA-5358752Reactome: R-HSA-5467337Reactome: R-HSA-5467340Reactome: R-HSA-5467348Reactome: R-HSA-5663220Reactome: R-HSA-5673000Reactome: R-HSA-5675221Reactome: R-HSA-6811558Reactome: R-HSA-68877Reactome: R-HSA-9634600Reactome: R-HSA-9648025 |
| Cellular Localisation | CytoplasmNucleusNuclear In InterphaseNuclear During Mitosis |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Phosphatase 2a 56 Kda Regulatory Subunit Delta Isoform antibodyAnti-Pp2a B Subunit Isoform B'-Delta antibodyAnti-Pp2a B Subunit Isoform B56-Delta antibodyAnti-Pp2a B Subunit Isoform Pr61-Delta antibodyAnti-Pp2a B Subunit Isoform R5-Delta antibodyAnti-PPP2R5D antibody |
Information sourced from Uniprot.org