| Short Description : | Rabbit polyclonal anti-Protein phosphatase 1 regulatory subunit 3A (647-696 aa) for use in WB and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PPP1R3A |
| Gene ID: | 5506 |
| Uniprot ID: | PPR3A_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human PPP1R3A at the amino acid range 647-696 |
| Immunogen Region: | 647-696 aa |
| Specificity: | PPP1R3A Polyclonal Antibody detects endogenous levels of PPP1R3A protein. |
| Post Translational Modifications | Phosphorylation at Ser-46 by ISPK stimulates the dephosphorylation of glycogen synthase and phosphorylase kinase. |
| Function | Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Plays an important role in glycogen synthesis but is not essential for insulin activation of glycogen synthase. |
| Protein Name | Protein Phosphatase 1 Regulatory Subunit 3aProtein Phosphatase 1 Glycogen-Associated Regulatory SubunitProtein Phosphatase Type-1 Glycogen Targeting SubunitRg1 |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Protein Phosphatase 1 Regulatory Subunit 3a antibodyAnti-Protein Phosphatase 1 Glycogen-Associated Regulatory Subunit antibodyAnti-Protein Phosphatase Type-1 Glycogen Targeting Subunit antibodyAnti-Rg1 antibodyAnti-PPP1R3A antibodyAnti-PP1G antibody |
Information sourced from Uniprot.org
