| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PPP1R14B |
| Gene ID: | 26472 |
| Uniprot ID: | PP14B_HUMAN |
| Immunogen Region: | 68-147 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 68-147 of human PPP1R14B (NP_619634.1). |
| Immunogen Sequence: | RLNLEEWILEQLTRLYDCQE EEIPELEIDVDELLDMESDD ARAARVKELLVDCYKPTEAF ISGLLDKIRGMQKLSTPQKK |
| Tissue Specificity | Ubiquitous. Expressed at low levels. |
| Post Translational Modifications | Phosphorylated primarily on Thr-57 by PKC (in vitro). An unknown Ser is also phosphorylated by PKC (in vitro). |
| Function | Inhibitor of PPP1CA. Has over 50-fold higher inhibitory activity when phosphorylated. |
| Protein Name | Protein Phosphatase 1 Regulatory Subunit 14bPhospholipase C-Beta-3 Neighbouring Gene Protein |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Protein Phosphatase 1 Regulatory Subunit 14b antibodyAnti-Phospholipase C-Beta-3 Neighbouring Gene Protein antibodyAnti-PPP1R14B antibodyAnti-PLCB3N antibodyAnti-PNG antibody |
Information sourced from Uniprot.org