| Host: | Rabbit |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-E3 ubiquitin-protein ligase PPP1R11 (71-120 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PPP1R11 |
| Gene ID: | 6992 |
| Uniprot ID: | PP1RB_HUMAN |
| Immunogen Region: | 71-120 aa |
| Specificity: | Tctex5 Polyclonal Antibody detects endogenous levels of Tctex5 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human PPP1R11 at the amino acid range 71-120 |
| Post Translational Modifications | Auto-ubiquitinated. |
| Function | Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2. Inhibitor of protein phosphatase 1. |
| Protein Name | E3 Ubiquitin-Protein Ligase Ppp1r11Hemochromatosis Candidate Gene V ProteinHcg VProtein Phosphatase 1 Regulatory Subunit 11Protein Phosphatase Inhibitor 3 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Ppp1r11 antibodyAnti-Hemochromatosis Candidate Gene V Protein antibodyAnti-Hcg V antibodyAnti-Protein Phosphatase 1 Regulatory Subunit 11 antibodyAnti-Protein Phosphatase Inhibitor 3 antibodyAnti-PPP1R11 antibodyAnti-HCGV antibodyAnti-TCTE5 antibody |
Information sourced from Uniprot.org
