| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Serine/threonine-protein phosphatase 1 regulatory subunit 10 is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PPP1R10 |
| Gene ID: | 5514 |
| Uniprot ID: | PP1RA_HUMAN |
| Specificity: | PP1RA Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from part of the human protein |
| Post Translational Modifications | Phosphorylated on Ser-398 by PKA within the region necessary for interaction with PPP1CA. |
| Function | Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers. |
| Protein Name | Serine/Threonine-Protein Phosphatase 1 Regulatory Subunit 10 Mhc Class I Region Proline-Rich Protein Cat53 Pp1-Binding Protein Of 114 Kda Phosphatase 1 Nuclear Targeting Subunit Protein Fb19 P99 |
| Cellular Localisation | Nucleus Found In Discrete Nucleoplasmic Bodies And Within Nucleoli Associates With Chromatin During Interphase Excluded From Condensed Chromosomes During Early Mitosis And Is Reloaded Onto Chromosomes At The Late Telophase |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Phosphatase 1 Regulatory Subunit 10 antibody Anti-Mhc Class I Region Proline-Rich Protein Cat53 antibody Anti-Pp1-Binding Protein Of 114 Kda antibody Anti-Phosphatase 1 Nuclear Targeting Subunit antibody Anti-Protein Fb19 antibody Anti-P99 antibody Anti-PPP1R10 antibody Anti-CAT53 antibody Anti-FB19 antibody Anti-PNUTS antibody |
Information sourced from Uniprot.org