| Post Translational Modifications | Phosphorylated on Ser-398 by PKA within the region necessary for interaction with PPP1CA. |
| Function | Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers. |
| Protein Name | Serine/Threonine-Protein Phosphatase 1 Regulatory Subunit 10Mhc Class I Region Proline-Rich Protein Cat53Pp1-Binding Protein Of 114 KdaPhosphatase 1 Nuclear Targeting SubunitProtein Fb19P99 |
| Cellular Localisation | NucleusFound In Discrete Nucleoplasmic Bodies And Within NucleoliAssociates With Chromatin During InterphaseExcluded From Condensed Chromosomes During Early Mitosis And Is Reloaded Onto Chromosomes At The Late Telophase |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Phosphatase 1 Regulatory Subunit 10 antibodyAnti-Mhc Class I Region Proline-Rich Protein Cat53 antibodyAnti-Pp1-Binding Protein Of 114 Kda antibodyAnti-Phosphatase 1 Nuclear Targeting Subunit antibodyAnti-Protein Fb19 antibodyAnti-P99 antibodyAnti-PPP1R10 antibodyAnti-CAT53 antibodyAnti-FB19 antibodyAnti-PNUTS antibody |
Information sourced from Uniprot.org
