| Short Description : | Mouse monoclonal anti-PPME1 (1-386aa) for use in ELISA and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | ELISA/WB |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | AT29G3 |
| Isotype: | IgG1k |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | By protein-A affinity chromatography |
| Formulation: | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PPME1 |
| Gene ID: | 51400 |
| Uniprot ID: | PPME1_HUMAN |
| Accession Number: | NP_057231 |
| Immunogen: | Recombinant human PPME1 (1-386aa) purified from E. coli |
| Immunogen Region: | 1-386aa |
| Post Translational Modifications | Phosphorylated by SIK1 following increases in intracellular sodium, leading to dissociation from the protein phosphatase 2A (PP2A) complex and subsequent dephosphorylation of sodium/potassium-transporting ATPase ATP1A1. |
| Function | Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme. |
| Protein Name | Protein Phosphatase Methylesterase 1Pme-1 |
| Database Links | Reactome: R-HSA-69273 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Protein Phosphatase Methylesterase 1 antibodyAnti-Pme-1 antibodyAnti-PPME1 antibodyAnti-PME1 antibodyAnti-PP2593 antibodyAnti-PRO0750 antibody |
Information sourced from Uniprot.org
