Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: |
Monoclonal |
Clone ID: |
S5751RM |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
Purification: |
Affinity purification |
Concentration: |
Lot specific |
Dilution Range: |
WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
PPM1E |
Gene ID: |
22843 |
Uniprot ID: |
PPM1E_HUMAN |
Immunogen Region: |
500-600 |
Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 500-600 of human PPM1E (Q8WY54). |
Immunogen Sequence: |
ESDWTENSFQGGQEDGGDDK ENHGECKRPWPQHQCSAPAD LGYDGRVDSFTDRTSLSPGS QINVLEDPGYLDLTQIEASK PHSAQFLLPVEMFGPGAPKK A |
Function | Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2. Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Dephosphorylates PRKAA2. |
Protein Name | Protein Phosphatase 1eCa(2+/Calmodulin-Dependent Protein Kinase Phosphatase NCamkp-NCamkp-NucleusCamknPartner Of Pix 1Partner Of Pix-AlphaPartner Of Pixa |
Database Links | Reactome: R-HSA-9617324 |
Cellular Localisation | NucleusCytoplasmA Truncated FormMajor FormWith The C-Terminal Part MissingIs Mostly Found In The Cytoplasm And A Little In The NucleusThe Full-LengthMinor FormIs Found In The Nucleus |
Alternative Antibody Names | Anti-Protein Phosphatase 1e antibodyAnti-Ca(2+/Calmodulin-Dependent Protein Kinase Phosphatase N antibodyAnti-Camkp-N antibodyAnti-Camkp-Nucleus antibodyAnti-Camkn antibodyAnti-Partner Of Pix 1 antibodyAnti-Partner Of Pix-Alpha antibodyAnti-Partner Of Pixa antibodyAnti-PPM1E antibodyAnti-CAMKN antibodyAnti-KIAA1072 antibodyAnti-POPX1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance