| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PPL (1-130) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:100-1:500 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PPL |
| Gene ID: |
5493 |
| Uniprot ID: |
PEPL_HUMAN |
| Immunogen Region: |
1-130 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human PPL (NP_002696.3). |
| Immunogen Sequence: |
MNSLFRKRNKGKYSPTVQTR SISNKELSELIEQLQKNADQ VEKNIVDTEAKMQSDLARLQ EGRQPEHRDVTLQKVLDSEK LLYVLEADAAIAKHMKHPQG DMIAEDIRQLKERVTNLRGK HKQIYRLAVK |
| Tissue Specificity | Expressed in stratified squamous epithelia and in some other epithelia. |
| Function | Component of the cornified envelope of keratinocytes. May link the cornified envelope to desmosomes and intermediate filaments. May act as a localization signal in PKB/AKT-mediated signaling. |
| Protein Name | Periplakin190 Kda Paraneoplastic Pemphigus Antigen195 Kda Cornified Envelope Precursor Protein |
| Database Links | Reactome: R-HSA-6809371Reactome: R-HSA-8851680 |
| Cellular Localisation | Cell JunctionDesmosomeCytoplasmCytoskeletonCell Membrane |
| Alternative Antibody Names | Anti-Periplakin antibodyAnti-190 Kda Paraneoplastic Pemphigus Antigen antibodyAnti-195 Kda Cornified Envelope Precursor Protein antibodyAnti-PPL antibodyAnti-KIAA0568 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
