Anti-PPFIA2 antibody (49-99 aa) (STJ195079)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human LIPA2 at the amino acid range 49-99
General Information
| Short Description | Rabbit polyclonal anti-Liprin-alpha-2 (49-99 aa) for use in WB, ELISA and IHC in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PPFIA2 |
| Gene ID | 8499 |
| Uniprot ID | LIPA2_HUMAN |
| Immunogen | Synthesized peptide derived from the human LIPA2 at the amino acid range 49-99 |
| Immunogen Region | 49-99 aa |
| Specificity | This antibody detects endogenous levels of LIPA2 at Human/Mouse |
Additional Info
| Function | Alters PTPRF cellular localization and induces PTPRF clustering. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. In neuronal cells, is a scaffolding protein in the dendritic spines which acts as immobile postsynaptic post able to recruit KIF1A-driven dense core vesicles to dendritic spines. |
| Protein Name | Liprin-Alpha-2Protein Tyrosine Phosphatase Receptor Type F Polypeptide-Interacting Protein Alpha-2Ptprf-Interacting Protein Alpha-2 |
| Database Links | Reactome: R-HSA-181429Reactome: R-HSA-181430Reactome: R-HSA-210500Reactome: R-HSA-212676Reactome: R-HSA-264642Reactome: R-HSA-388844 |
| Cellular Localisation | CytoplasmCell SurfaceCell ProjectionDendritic SpineColocalizes With Ptprf At The Cell Surface |
| Alternative Antibody Names | Anti-Liprin-Alpha-2 antibodyAnti-Protein Tyrosine Phosphatase Receptor Type F Polypeptide-Interacting Protein Alpha-2 antibodyAnti-Ptprf-Interacting Protein Alpha-2 antibodyAnti-PPFIA2 antibody |
Information sourced from Uniprot.org