Anti-PPFIA2 antibody (49-99 aa) (STJ195079)

SKU:
STJ195079
€58.80 - €313.20
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Short Description :Rabbit polyclonal anti-Liprin-alpha-2 (49-99 aa) for use in WB, ELISA and IHC in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/ELISA/IHC
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
IHC-P 1:50-300
ELISA 2000-20000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:PPFIA2
Gene ID:8499
Uniprot ID:LIPA2_HUMAN
Immunogen:Synthesized peptide derived from the human LIPA2 at the amino acid range 49-99
Immunogen Region:49-99 aa
Specificity:This antibody detects endogenous levels of LIPA2 at Human/Mouse
Function Alters PTPRF cellular localization and induces PTPRF clustering. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. In neuronal cells, is a scaffolding protein in the dendritic spines which acts as immobile postsynaptic post able to recruit KIF1A-driven dense core vesicles to dendritic spines.
Protein Name Liprin-Alpha-2
Protein Tyrosine Phosphatase Receptor Type F Polypeptide-Interacting Protein Alpha-2
Ptprf-Interacting Protein Alpha-2
Database Links Reactome: R-HSA-181429
Reactome: R-HSA-181430
Reactome: R-HSA-210500
Reactome: R-HSA-212676
Reactome: R-HSA-264642
Reactome: R-HSA-388844
Cellular Localisation Cytoplasm
Cell Surface
Cell Projection
Dendritic Spine
Colocalizes With Ptprf At The Cell Surface
Alternative Antibody Names Anti-Liprin-Alpha-2 antibody
Anti-Protein Tyrosine Phosphatase Receptor Type F Polypeptide-Interacting Protein Alpha-2 antibody
Anti-Ptprf-Interacting Protein Alpha-2 antibody
Anti-PPFIA2 antibody

Information sourced from Uniprot.org