| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PPFIA1 |
| Gene ID: | 8500 |
| Uniprot ID: | LIPA1_HUMAN |
| Immunogen Region: | 660-800 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 660-800 of human PPFIA1 (NP_003617.1). |
| Immunogen Sequence: | IESRVGSGSLDNLGRFRSMS SIPPYPASSLASSSPPGSGR STPRRIPHSPAREVDRLGVM TLLPPSREEVRDDKTTIKCE TSPPSSPRALRLDRLHKGAL HTVSHEDIRDIRNSTGSQDG PVSNPSSSNSSQDSLHKAPK K |
| Tissue Specificity | Ubiquitous. |
| Function | May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. |
| Protein Name | Liprin-Alpha-1Lar-Interacting Protein 1Lip-1Protein Tyrosine Phosphatase Receptor Type F Polypeptide-Interacting Protein Alpha-1Ptprf-Interacting Protein Alpha-1 |
| Database Links | Reactome: R-HSA-181429Reactome: R-HSA-181430Reactome: R-HSA-210500Reactome: R-HSA-212676Reactome: R-HSA-264642Reactome: R-HSA-388844 |
| Cellular Localisation | CytoplasmCell CortexColocalizes With Ptprf Near Focal Adhesions |
| Alternative Antibody Names | Anti-Liprin-Alpha-1 antibodyAnti-Lar-Interacting Protein 1 antibodyAnti-Lip-1 antibodyAnti-Protein Tyrosine Phosphatase Receptor Type F Polypeptide-Interacting Protein Alpha-1 antibodyAnti-Ptprf-Interacting Protein Alpha-1 antibodyAnti-PPFIA1 antibodyAnti-LIP1 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and ANKRD52 knockout (KO) 293T cells, using [KO Validated] ANKRD52 Rabbit polyclonal antibody (STJ11100834) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89769/358241/STJ11100834_1__55275.1713122574.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and ANKRD52 knockout (KO) 293T cells, using [KO Validated] ANKRD52 Rabbit polyclonal antibody (STJ11100834) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
